preparation of [111in]-bleomycin radiopharmaceutical [persian]

Preparation of [111In]-Bleomycin radiopharmaceutical [Persian]

In this study, the preparation of 111In-Bleomycin complex was optimized for temperature, time, concentration and pH during several experiments. The results showed that by the addition of bleomycin to 111In-InCl3 sample (dried under flow of N2) and heating the mixture up to 90-100°C the radiopharmaceutical can be obtained in 99.5% yield and a specific activity of 1.745 Ci/mmol. The final s...

Assessment the Effect of Kidney Internal Structure on Gamma Absorbed Dose of Radiopharmaceutical 111In-DTPA

Large quantities of radiopharmaceuticals prescribed for treatment and diagnosis are excreted through kidney. Therefore, radiation unwanted dose is created in kidney. As a result, exact calculation of prescribed radiopharmaceuticals amount is important. Monte Carlo method is used for simulation of radiation transport in body due to random nature of radiation. In this research, for the first time...

Tektrotyd kit for radiopharmaceutical preparation ENG PAR

Assessment the Effect of Kidney Internal Structure on Gamma Absorbed Dose of Radiopharmaceutical 111In-DTPA

Large quantities of radiopharmaceuticals prescribed for treatment and diagnosis are excreted through kidney. Therefore, radiation unwanted dose is created in kidney. As a result, exact calculation of prescribed radiopharmaceuticals amount is important. Monte Carlo method is used for simulation of radiation transport in body due to random nature of radiation. In this research, for the first time...

Technetium-99m radiopharmaceutical preparation problems: 12 years of experience.

OBJECTIVE Chemical reactions involved in preparing 99mTc radiopharmaceuticals occasionally result in products of substandard purity. A retrospective examination of preparation problems that occurred in the author's institution was conducted to better define the incidence, recognize patterns and identify causes of substandard 99mTc radiopharmaceutical products. METHODS All 99mTc radiopharmaceu...

Dose from syringe procedures during technetium-99m radiopharmaceutical preparation.

UNLABELLED We examined the dose from 99mTc contained in syringes and shielded vials to assess in detail the dose burdens in a central pharmacy. METHODS Absorbed-dose rates at the end of the plunger of a shielded syringe, when 99mTc is contained either in the syringe or in a shielded vial from which the activity would be drawn, were measured with CaF2 dosimeters. The dose rates also were calcu...